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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
10.91
Human Site:
S567
Identified Species:
21.82
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S567
V
T
A
Y
D
L
L
S
N
R
V
I
K
K
P
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S696
V
T
A
Y
D
L
L
S
N
R
V
I
K
K
P
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
E521
P
V
K
I
L
V
P
E
K
S
L
P
C
K
V
Dog
Lupus familis
XP_536002
930
105612
S567
L
T
A
Y
D
L
I
S
S
R
V
V
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
P545
G
D
L
D
C
R
P
P
G
T
G
Q
S
L
K
Rat
Rattus norvegicus
NP_001009535
919
103710
A566
A
V
K
K
P
M
S
A
C
A
L
F
I
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
R557
K
G
S
S
F
W
S
R
T
G
T
K
L
E
P
Chicken
Gallus gallus
NP_001006508
916
103017
I562
Y
D
L
I
S
G
R
I
I
R
K
S
K
S
A
Frog
Xenopus laevis
NP_001079545
925
103654
L566
K
R
A
I
K
K
P
L
S
A
E
E
H
F
I
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
T557
K
A
S
P
Q
D
V
T
A
A
A
K
E
R
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
S424
N
C
L
Q
S
T
Q
S
I
P
P
E
S
S
R
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
L572
N
S
G
L
Q
P
K
L
A
E
D
P
S
G
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
6.6
73.3
N.A.
0
0
N.A.
6.6
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
0
26.6
N.A.
20
13.3
13.3
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
34
0
0
0
0
9
17
25
9
0
0
0
9
% A
% Cys:
0
9
0
0
9
0
0
0
9
0
0
0
9
0
0
% C
% Asp:
0
17
0
9
25
9
0
0
0
0
9
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
9
0
9
9
17
9
9
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
9
9
9
0
0
9
0
0
9
9
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
25
0
0
9
9
17
0
0
17
9
0
9
% I
% Lys:
25
0
17
9
9
9
9
0
9
0
9
17
34
34
9
% K
% Leu:
9
0
25
9
9
25
17
17
0
0
17
0
9
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% N
% Pro:
9
0
0
9
9
9
25
9
0
9
9
17
0
0
34
% P
% Gln:
0
0
0
9
17
0
9
0
0
0
0
9
0
9
0
% Q
% Arg:
0
9
0
0
0
9
9
9
0
34
0
0
0
9
9
% R
% Ser:
0
9
17
9
17
0
17
34
17
9
0
9
25
17
0
% S
% Thr:
0
25
0
0
0
9
0
9
9
9
9
0
0
0
0
% T
% Val:
17
17
0
0
0
9
9
0
0
0
25
9
0
0
9
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _